The osler medical handbook -john hopkin
Section VIII – Infectious DiseasesSection Editors:Christopher Hoffmann, MD, MPH Nicola Zetola, MDChapter 53 – Fever of Unknown OriginScott Kim, MD Rachel Damico, MD, PhD Paul Auwaerter, MDFAST FACTS ▪ The contemporary understanding of fever of unknown origin (FUO) is derived from Petersdorf and Beeson's 1961 characterization of FUO. A stringent definition of FUO is composed of the following criteria[1]: temperature higher than 38.3° C measured on several occasions, 3-week duration (to exclude self-limiting fevers), negative blood cultures, no apparent explanation, and three outpatient visits or three hospital days. ▪ Infections, malignancies, and noninfectious inflammatory diseases account for the majority of cases of FUO. ▪ In patients older than 65 years, temporal arteritis should be considered early in any evaluation. ▪ Patients with FUO who remain undiagnosed after exhaustive study usually have a favorable prognosis. In one study, in a cohort of 61 patients with FUO discharged without diagnosis, the 5-year mortality rate was only 3.2%.[2]…


![[ Porsche Centric ] Bình Minh | Juricii & Remi |](https://truyen4u.com/images/porsche-centric-binh-minh-juricii-remi-319142098.webp)

![[TransShortFic] HopeMin - Love is not over (Ba mươi câu hỏi)](https://truyen4u.com/images/transshortfic-hopemin-love-is-not-over-ba-muoi-cau-hoi-88894340.webp)

![[NoéVani] I slept well](https://truyen4u.com/images/noevani-i-slept-well-167265316.webp)

![Wuthering Wave [Divinity-Civilization-Echo of the past]](https://truyen4u.com/images/wuthering-wave-divinity-civilization-echo-of-the-past-401886826.webp)

